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    Run & Done with PaSER

    PaSER 1.0

    PaSER 1.0 is a GPU powered real-time database search platform providing parallel computing power and real-time database search results for bottom-up proteomics.

    Immediate Results!

    Real-time results = efficiency

    paser

    Highlights

    PaSER is efficiency and savings

    Real-time results inform you of current instrument and sample status

    Analysis Time
    Database searches take time, eliminate this step with uncompromised search results as soon as the acquisition is complete.
    Instrument Time
    Be sure every minute count’s, with PaSER you can be assured that your instrument time is spent in the most meaningful way.
    Precious Samples
    Save those precious samples! Whether they are single cell or clinical, PaSER’s smarts will make sure they are not wasted needlessly.
    Costs
    Instrument time, reagents and sample preparation are costly. PaSER and Run & Done will save money because you are assured you are producing meaningful data.

    Features

    PaSER 1.0

    4D-Proteomics? with real-time search results and smart acquisition

    Break the data analysis bottleneck by integrating real-time database search and smart acquisition provided by PaSER

    Universally available

    • All current and future timsTOF Pro and fleX platforms are PaSER accessible

    4D-Proteomics?

    • CCS-aware data is rich, even so real-time database search capabilities are a reality with PaSER including with PTMs like phosphorylation

    Massive parallelization with GPU power

    • PaSER is GPU powered, provide massive compute power across thousands of CUDA cores

    PaSER Data Review

    • View the intricate details of your data from the high level experimental information to a specific fragment ion spectrum of interest with confidence from the integrated viewer onboard all PaSER boxes
    Smarts
    • PaSER is smart, where a user defined qualification of proteins or peptides at the end of a sample acquisition determines the progression of your sample queue, this checks suitability, save precious samples, expensive consumables and instrument time

    Benefits

    PaSER 1.0

    Benefit from time and cost savings

    • No more worrying about injecting those precious samples.
    • No more worrying of wasted instrument time.
    • No more worrying about those samples with expensive reagents and sample prep, only to inject on a poor performing system.?
    • No more waiting for the QC runs to determine system suitability.
    • No more waiting for search results during method development.

    • Precious samples
    • Instrument time
    • Expensive reagents
    • Sample prep time
    • Analysis time
    • Waiting time

    Full-fledged database search in less than 8 ms
    PaSER provides consistent results obtained from the real-time search, identical to offline search of the same data. Since the database search algorithm is run on the GPU, the search times are negligible compared to CPU based searches. In addition to real-time search the opportunity to search a larger space for specific applications, including peptidome studies, becomes reality.

    Blazing search speed. A) A single injection of a human cell lystate analyzed against the forward and reverse sequences of the Uniprot Human fasta file with upto 6 PTMs using either ProLuCID or ProLuCID-GPU search algorithm. B) PaSER can process MSMS spectra with an average search time ~1ms. C) PaSER search results are nearly identical whether done in a real-time manner or offline.

    Webinars

    Testimonials

    “Innovative software tools are a necessity to address unanswered biological questions with mass spectrometry. The trapped ion mobility functionality and the robustness of the timsTOF Pro offer unique bottom-up proteomics capabilities that can be effectively used to study many diseases.”

    Professor John Yates III, the Ernest W. Hahn Professor at The Scripps Research Institute in La Jolla, California

    More Information

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